New at-home options detect 83% of colorectal cancers without prep, sedation, or time off work.
The American Cancer Society just approved blood and stool tests as legitimate alternatives to colonoscopy for colorectal cancer screening. The blood test catches 83% of cancers by detecting tumor DNA circulating in your bloodstream. Two new at-home stool tests find cancer markers with similar accuracy. All three options require no bowel prep, no sedation, and no day off work.
This matters because one-third of eligible adults skip colonoscopy screening entirely—that's 20 million people. The new tests aren't quite as thorough as colonoscopy (which remains the gold standard), but they're exponentially better than no screening at all. Any positive result still requires a follow-up colonoscopy, but these tests could catch thousands of early-stage cancers that would otherwise go undetected.
Colorectal cancer is now the leading cancer killer for people under 50, with rates climbing steadily. When caught early, survival rates exceed 90%. The blood test happens every three years, the stool tests annually. For people who've been putting off screening due to colonoscopy anxiety or logistics, these alternatives remove the biggest barriers to potentially life-saving early detection.
What You Can Actually Do Today
- Ask your doctor about blood-based screening at your next appointment if you're 45+ and have avoided colonoscopy
- Research whether your insurance covers the new stool tests (most do) if you're due for screening
- Schedule the colonoscopy if you've been putting it off—it's still the most comprehensive option
Positive results from blood or stool tests require colonoscopy follow-up within six months.